Immunity-inflammation

The Relationship Between the Intestinal Microbiome, Dysbiosis, and Inflammation in Dogs and Cats

Speakers:

Jan Suchodolski, MedVet, DrVetMed, PhD, AGAF, DACVM

Event date: 11 April 2024

Chronic enteropathy of dogs and cats is a syndrome with a complex pathophysiology that includes changes in the immune system, intestinal function, and the intestinal microbiome. The many overlapping unspecific features of chronic enteropathy often result from persistent dysbiosis and irreversible changes in intestinal function. The extent of inflammation and dysbiosis varies among patients, and is likely the reason why response to therapy varies from patient to patient.

In this session, Dr. Jan Suchodolski discusses the need to expand basic understanding of gastrointestinal tract physiology, changes in the intestinal microbiome and fecal metabolomics in chronic enteropathy, and why malabsorption may be a more significant driver of dysbiosis than inflammation.

Related Content

New Approaches to Immunomodulation and Diagnostics

Alison Manchester, DVM, MS, DACVIM (SAIM)

Chronic enteropathy in dogs is a common clinical problem with a poorly understood pathogenesis. Learn how transcriptomic studies are providing new insights into the mechanisms that contribute to clinical signs of chronic enteropathy.

VIEW EVENT 30-60 minutes

Gut Barrier Function and Immune Tolerance in Healthy and Allergic Dogs

Stefan Unterer, Dr. med. vet., Dr. habil, Dipl. ECVIM-CA

Discover what is currently known about the role of acute intestinal injury in the development of chronic enteropathies and food allergies in dogs.

VIEW EVENT 30-60 minutes

Impact of Nutrition on Allergy and Tolerance in Dogs

Katie Tolbert, DVM, PhD, DACVIM (SAIM, Nutrition)

Epithelial barrier dysfunction, oxidant injury, and inflammation are common to both atopic dermatitis and chronic inflammatory enteropathy in dogs. These shared features are attractive targets for nutritional approaches to patient management.

VIEW EVENT 30-60 minutes

Comparative Aspects of Nutrient Effects on the Intestinal Microbiome in Humans and Other Animals

Christian Hoffmann, PhD

Scientists’ understanding of the host-microbiome relationship has evolved substantially during the past 15 years, revealing a complex interplay among diet, host genetics, microbiota, and health.

VIEW EVENT 30-60 minutes