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Right lateral thoracic radiograph of a small dog in ACVIM Stage C, heart failure.


Improved preservation of body weight
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TEST - SENIOR PET COGNITION: TIPS ON MANAGING CASES AND THE ROLE OF NUTRITION
- Adipose tissue is an active endocrine organ, secreting hormones, cytokines, and other protein factors—collectively called adipokines—that have biological influence throughout the body.
- Adipokines that affect insulin resistance, inflammation, oxidative stress, and other biological functions are altered in obesity.
- Weight loss is linked with reduction of adipokines that are biomarkers for inflammation.
Putting the science into practice
Antibiotics such as metronidazole and amoxicillin-clavulanate can have long-lasting, negative impacts on the microbiome, and their use should be avoided unless necessary and with the principles of antimicrobial stewardship in mind.3,4
For dogs with clinical signs consistent with antibiotic-responsive diarrhea or small intestinal bacterial overgrowth, the probiotic E. faecium SF68 combined with a therapeutic diet improves diarrhea without the administration of antibiotics. Consider trying this approach before administering antimicrobials to these cases.
Metronidazole does not inactivate the probiotic E. faecium SF68, making the probiotic suitable for co-administration. When administering amoxicillin-clavulanate to cats, the administration of E. faecium SF68 or a synbiotic (E. faecium SF68 and psyllium) helps mitigate diarrhea.