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CYTOKINES
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Canine osteoarthritis
One in five adult dogs suffers from osteoarthritis, a progressive and painful condition that reduces mobility and quality of life.1
Purina's research
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In this study, the mean age at which 50% of the dogs in each group first required long-term treatment for osteoarthritis was significantly (P < 0.01) later for the lean-fed group (13.3 years) than for the control-fed group (10.3 years).2
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By two years of age, the frequency of hip dysplasia in the lean-fed dogs was 50% less than in the control group, and the hip dysplasia was much less severe.5
At the end of the study, only 50% of the lean-fed group had radiographic signs of hip osteoarthritis compared to 83% of control-fed dogs.3
Maintaining a lean body condition also resulted in lower prevalence and severity of shoulder osteoarthritis and elbow osteoarthritis, respectively, at 8 years of age.4
Key thing to remember
- Dogs fed to maintain a lean body condition from puppyhood throughout life had significantly less osteoarthritis, in addition to a longer lifespan.
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Find out more
- Johnston, S. A. (1997). Osteoarthritis: Joint anatomy, physiology, and pathobiology. Veterinary Clinics of North America: Small Animal Practice, 27(4), 699–723.
- Kealy, R. D., Lawler, D. F., Ballam, J. M., Mantz, S. L., Biery, D. N., Greeley, E. H., Lust, G., Segre, M., Smith G. K., & Stowe, H. D. (2002). Effects of diet restriction on life span and age-related changes in dogs. Journal of the American Veterinary Medical Association, 220(9), 1315–1320.
- Smith, G. K., Paster, E. R., Powers, M. Y., Lawler, D. F., Biery, D. N., Shofer, F. S., McKelvie, P. J., & Kealy, R. D. (2006). Lifelong diet restriction and radiographic evidence of osteoarthritis of the hip joint in dogs. Journal of the American Veterinary Medical Association, 229(5), 690–693.
- Kealy, R. D., Lawler, D. F., Ballam, J. M., Lust, G., Biery, D. N., Smith, G. K., & Mantz, S. L. (2000). Evaluation of the effect of limited food consumption on radiographic evidence of osteoarthritis in dogs. Journal of the American Veterinary Medical Association, 217(11), 1678–1680.
- Kealy, R. D., Olsson, S. E., Monti, K. L., Lawler, D. F., Biery, D. N., Helms, R. W., Lust, G., & Smith, G. K. (1992). Effects of limited food consumption on the incidence of hip dysplasia in growing dogs. Journal of the American Veterinary Medical Association, 201(6), 857–863.