Resident E. coli: A Frenemy Within
Speaker:
Kenneth Simpson, BCM&S, PhD, DACVIM, Dipl ECVIM-CA
Event date: 6–7 November 2024 Virtual Event
Escherichia coli colonizes humans, puppies, and kittens early in life. Genetically diverse, E. coli can be a symbiont, opportunistic pathogen, or pathogen with variable pathogenicity.
E. coli is normally present in the gastrointestinal (GI) tract, where it is highly adapted to life at the mucosal interface. Colonization density and spatial distribution of E. coli differ in health and disease. In healthy patients, E. coli resides in the mucus layer. However, in disease, bacteria adhere to and colonize the intestinal epithelium.
In this lecture, Dr. Simpson discusses what factors can trigger E. coli proliferation and virulence and what strategies veterinarians can use to combat E. coli-associated dysbiosis.
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