can-summit-2023

Understanding How Age-Associated Changes of the Immune System Lead to Immune Dysfunction

Speaker:

Donald B. Palmer, PhD, PGCAP, FHEA, FRSB 

Event date: 25 May 2023 Lausanne, Switzerland 

Advanced aging correlates with a reduced ability to mount an effective immune response, a process known as immunosenescence. While the precise mechanisms of immunosenescence have not been fully explained, both innate and adaptive immunity show age-associated decline in function.  

Thymic involution is one of the most recognisable changes in the aging immune system and is believed to be intimately linked to features of peripheral immunosenescence. The mechanism of age-associated thymic involution is still not fully identified, but evidence suggests it likely involves both intrinsic and extrinsic defects. 

Related Content

Implications of Immunosenescence and Inflammageing for Immunization of Older Individuals

Graham Pawelec, MA, PhD (Cantab), FGSA

An overview of how age-related changes in the human immune system can add to the understanding of companion animal aging and immune function.

View Event 30-60 minutes

Diet and Immune Function

Caroline Childs, BSc (Hons), PhD, RNutr

An introduction to the links between diet and immune function and the evidence for using diet in the prevention or management of health conditions.

View Event 30-60 minutes

Investigating the Potential of Targeting Microbiome Dysbiosis for Combatting Immunosenescence

Niharika A. Duggal, BSc (Hons), PhD, PGCHE

Microbiome-based therapies, which offer a range of health benefits, are attracting interest as a target for anti-immune ageing therapies.

View Event 30-60 minutes

Panel Discussion: Immunosenescence: The Impact of Age on Immune Function

Donald B. Palmer, PhD, PGCAP, FHEA. FRSB, Graham Pawelec, MA, PhD (Cantab), FGSA, Caroline Childs, BSc (Hons), PhD, Rnutr, Niharika A. Duggal, BSc (Hons), PhD, PGCHE

Speakers at the 2023 Companion Animal Nutrition Summit answer questions and discuss topics related to Immunosenescence: The Impact of Age on Immune Function.

View Event 30-60 minutes